Principles Of Clinical Pharmacology

Author: Arthur J. Atkinson, Jr.
Publisher: Academic Press
ISBN: 0123854725
Size: 33.11 MB
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Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III

Competence Assessment Tools For Health System Pharmacies

Author: Lee B. Murdaugh
Publisher: ASHP
ISBN: 9781585283118
Size: 19.76 MB
Format: PDF, Kindle
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Since its original publication, Competence Assessment Tools for Health-System Pharmacies has continued to meet the changing needs of pharmacy directors and their staff. Designed as a complete human resource competence assessment program, this benchmark resource ensures pharmacies comply with the competence assessment standards of The Joint CommissionÔ. Newly updated and revised, Competence Assessment provides practical tools to assess and document an employee’s ability to perform assigned duties and meet Joint Commission human resource requirements. Save time and increase efficiency with this essential tool that supplements and reinforces staff knowledge in key competency areas. New to the Fourth Edition: Enhanced CD-ROM allows you to easily adapt many of the forms for your own practice including the job descriptions and orientation record. • Updated resources for customizing job descriptions, including job description, competence assessment summary, and performance evaluation templates for a Pharmacy Purchasing Technician. • Inclusion of a study guide for the emergency management chapter. • New chapters on intravenous to oral therapy conversion and antibiotic streamlining. • Expanded information in the hazardous materials chapter including the requirements of the Resource Conservation and Recovery Act (RCRA) and practice recommendations from the National Institute for Occupational Safety and Health (NIOSH) and ASHP. • Updated controlled substances chapter including information about the Combat Methamphetamine Epidemic Act. • New test questions in many chapters including use of a patient case report format for tests in the clinically-oriented chapters.

Low Dose Antibiotics Current Status And Outlook For The Future

Author: Robert Paul Hunter
Publisher: Frontiers E-books
ISBN: 2889193551
Size: 30.97 MB
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Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. However, we are currently at a watershed point as we face a growing crisis of antibiotic resistance among diverse pathogens. One area of intense interest is the impact of the application of antibiotics for uses other than the treatment of patients and the association with such utilization with emerging drug resistance. This Research Topic “Low- dose antibiotics: current status and outlook for the future” in Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy details various aspects of the wide ranging effects of antimicrobial therapy from areas such as the regulation of host responses to modulation of bacterial virulence factors to acquisition of antibiotic resistance genes.

The Interventional Cardiac Catheterization Handbook E Book

Author: Morton J. Kern
Publisher: Elsevier Health Sciences
ISBN: 145574042X
Size: 71.63 MB
Format: PDF, Mobi
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The newly updated Interventional Cardiac Catheterization Handbook helps you to effectively perform common therapeutic interventions. This convenient handbook provides full-color illustrations and videos showcasing up-to-date, step-by-step methods for the most widely practiced interventional cardiology procedures! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Review traditional procedures as well as more specialized interventions, including laser angioplasty, atherectomy, and stent implantation. Quickly access the information you need with the help of an easy-to-read outline format, which includes helpful tables and boldfaced key terms. An excellent complement to the 5th Edition of Kern's Cardiac Catheterization Handbook, the Interventional Cardiac Catheterization Handbook is also an ideal review tool for the boards. Make optimal use of the latest techniques with coverage of coronary interventions using radial access; advances in femoral closure devices; avoidance of restenosis; interventions for peripheral vascular disease; LV support devices for high-risk PCI; indications and potential pitfalls of new stents and approach to failing dialysis shunts. Effectively evaluate coronary and peripheral vascular disease with full coverage of non-angiographic imaging techniques including FFR, OCT, IVUS and the new tools to assess intravascular plaque composition. View online videos demonstrating Radial Access, Tandem Heart for High-Risk PCI, FFR for Serial Lesions, Thromboaspiration for STEMI, Management of Coronary Perforation, and more at www.expertconsult.com!

Biofilms Infection And Antimicrobial Therapy

Author: John L. Pace
Publisher: CRC Press
ISBN: 1420028235
Size: 40.95 MB
Format: PDF, ePub, Mobi
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Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange. Biofilms, Infection, and Antimicrobial Therapy provides an in-depth exploration of biofilms, offering broad background information, as well a detailed look at the serious concerns to which biofilm-associated infections give rise. Prosthetic device infections, such as those involving artificial heart valves, intravascular catheters, or prosthetic joints, are prime examples of biofilm-associated infections. With the increasing use of such devices in the modern practice of medicine, the prevalence of these infections is expected to increase. Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents. As biofilm-associated infections are particularly difficult to treat, they result in significant mortality, morbidity, and increased economic burden. Clearly, a better understanding of the pathogenesis of these infections and improved means for prevention and treatment are urgently needed! InBiofilms, Infection, and Antimicrobial Therapy, Drs Pace, Rupp, and Finch assemble the contributions of more than 50 of the world’s leading authorities on microbial biofilms who present recent findings on antibacterial tolerance and bacterial persistence associated with biofilms and discuses the implications of those findings with regard to human health. They explore the molecular mechanisms of bacterial adherence, biofilm formation, regulation of biofilm maintenance, and cell-to-cell communication and present the latest information on various treatment protocols that should aid physicians in the treatment of these refractory and often difficult-to-treat infections.