The volume of endoscopic biopsies being performed continues to grow rapidly and they now represent one of the most common specimens encountered in routine surgical pathology practice. It is essential to maintain the balance between the speed and accuracy while integrating emerging sophisticated pathology techniques into endoscopic biopsies in routine practice. Microscopic appearance is virtually diagnostic of certain diseases. In others a diagnosis may be rendered only after correlating the microscopic pattern with clinical clues aided by ancillary tests. This text provides a guide to systematic approach of endoscopic biopsies to render a safe, quick and accurate pathological diagnosis in an integrated manner as well as important information that pathologists and clinicians should know to get the best value of endoscopic biopsies. The first chapter introduces the key microscopic features that are normal and abnormal in the gut mucosa as appreciated in an endoscopic biopsy. The second chapter presents a general overview highlighting the neoplastic and non-neoplastic patterns that are common to the entire tubular gut. Because some patterns are common to many sites, an overarching chapter gives the reader a generalized approach, which will be further refined in subsequent site specific chapters. The disease etiologies of each pattern are discussed, with emphasis placed on the most common causes that will be encountered in clinical practice. The subsequent chapters that follow then concentrate on patterns encountered at specific anatomical locations. Under each anatomical location (esophagus, stomach, small intestine and large intestine) site specific patterns of both neoplastic and non-neoplastic conditions are described. Conditions that affect many sites in the gastrointestinal tract are discussed in detail in the most relevant site chapter, but are referred to in other chapters as the reaction pattern/s they produce at that site is discussed. Ancillary tests that are required for a diagnosis of some diseases in particular neoplastic conditions are listed with tips for interpretation. This is presented mostly in a table format to assist day-to-day quick reference. In keeping with recent advances of using small biopsies for testing clinically relevant bio markers, important information that the pathologists and clinicians need to know is highlighted in appropriate sites. Authored by experts in the field, each chapter is presented under headings that include diagnostic features, patterns with relevant endoscopic and clinical clues, traps and overlapping features, and appropriate ancillary tests including clinically relevant molecular signatures in endoscopic biopsies.
Gastrointestinal mucosal biopsies are an active part of the pathologist's day and have increased in the past few years as endoscopic screening has become more commonplace. This new full-color Second Edition of Biopsy Interpretation of the Gastrointestinal Tract Mucosa has been expanded into two concise, comprehensive volumes to offer more complete coverage of both non-neoplastic and neoplastic entities. Like the other books in the Biopsy Interpretation Series, these volumes are practical references for pathologists to use when making diagnostic decisions based on biopsy specimens. Volume 2 of this Second Edition focuses on interpretation of neoplastic gastrointestinal mucosal biopsies. Coverage is geared to daily practice and includes mucosal biopsies from the esophagus, stomach, small intestine, large intestine, and anus. A companion website will include all of the 300 print illustrations plus an additional 750 e-figures. Volume 1 focuses on non-neoplastic biopsies and published in November 2011.
This volume of the Biopsy Interpretation Series is a practical, superbly illustrated guide to interpreting gastrointestinal tract mucosal biopsies. The book describes and illustrates the distinguishing features of non-neoplastic lesions, polyps, and neoplasms of the esophagus, stomach, small intestine, colon, and anus. The author addresses the biopsy interpretation issues confronting pathologists in daily practice and offers advice on avoiding pitfalls in biopsy diagnosis. The up-to-date coverage includes detailed information on newly recognized serrated polyps. A bound-in CD-ROM contains 955 full-color digital images of common and rare entities, and includes a quiz mode that is ideal for board exam preparation.
This new volume of the Biopsy Interpretation Series is a practical, superbly illustrated guide to the technical and interpretive aspects of a frozen section. The focus is on use of the frozen section in intraoperative management of patients, particularly those with tumors. The authors give pathologists a thorough knowledge of the utility and limitations of a frozen section, the appropriate circumstances for doing one, the proper techniques, and the interpretation and reporting of results. The book features more than 300 full-color gross and microscopic images, with discussions of differential diagnosis. A companion Website will provide 300 additional figures, plus a test bank that is ideal for board exam preparation.
This book is primarily addressed to the needs of the trainee histopathologist. It is intended to bridge that gap between the descriptive histopathology taught as part of the undergraduate medical curriculum and the interpretative skills required of the diagnostician. My object is to convey the basic general principles, in theory and practice. Books are, however, only adjuncts to practical experience and not substitutes for it. Indeed, to obtain the maximum benefit from this book it is essential that the reader is actively involved in the work of a diagnostic laboratory. Only in this way can the trainee become thoroughly conversant with the rudiments of biopsy interpretation. To retain detailed knowledge of the histological appearances of the plethora of diseases and their permutations to which humans are subject is beyond the mental resources of most individuals. For this reason, histopathologists probably refer to books more often than do most other specialists. This book aims to provide a core of knowledge sufficient to master the fundamental aspects, while still encouraging the intelligent use of all those indispensable atlases, monographs, and fascicles for which there is no substitute.
The latest edition of the critically acclaimed Small Animal Endoscopy presents informative, practical, and up-to-date guidance on endoscopic indications, instrumentation, patient preparation, and techniques. Todd R. Tams and Clarence A. Rawlings, the foremost experts in veterinary endoscopy, provide the novice as well as the advanced practitioner with the information needed to deliver the safest, high-quality endoscopic services for small animals, including avian and exotics. Chapters are organized consistently and lavishly illustrated to help you easily find and understand key concepts and procedures. This edition includes a companion website with expert demonstrations of techniques. Enables you to deliver the safest, high quality care and a wider range of services to the pets of increasingly concerned and savvy owners. Features cutting-edge information on minimally invasive procedures to improve diagnostic accuracy, reduce operating time, improve success, minimize post-operative stress and pain, and promote faster healing. Helps you recognize the many indications for endoscopy in everyday practice. Covers a vast range of topics in a clear, concise and readable style. Describes instrumentation, examination, and sample procurement techniques in detail. Shows both normal and abnormal findings you may encounter during a procedure in an atlas of images in relevant chapters. Provides minimally invasive examination and surgical options for veterinarians treating uniquely sensitive avian and exotic patients. Provides step-by-step instructions on specific techniques. Helps beginners master endoscopic diagnosis and treatment and more experienced endoscopists utilize their endoscopic equipment to its fullest capacity.
Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.
Diagnostic Pathology of Infectious Disease presents a comprehensive, organ-based approach to the effective and accurate diagnosis of infectious diseases. Dr. Richard L. Kradin covers the latest information on H1N1, as well as the use of immunohistochemical stains, PCR, Immunoperoxidase, and other molecular techniques for a current representation of the field. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion so you can quickly identify and diagnose whatever you see. This reference is an invaluable tool for the accurate diagnosis of any infectious disease—from the common to the most challenging. Covers the latest techniques in immunohistochemistry and molecular genetics integrated throughout the text for comprehensive information on all investigative contexts relevant to ensuring diagnostic accuracy. Emphasizes the host responses critical in differential diagnosis to serve as a second opinion when non-infectious diagnoses mimic and confound the diagnosis of infection. Provides a complete visual guide to suspect lesions through superb, high-quality, full-color illustrations of key aspects of various diseases that facilitate the rapid identification of biopsy specimen. Presents contents organized by organ as opposed to pathogen to more effectively address diagnostic and management issues. Features tables that list differential diagnosis for each lesion for quick summaries of key points in problem areas. Highlights morphological characteristics and landmarks of tissue samples throughout the text for easy access to information necessary for signing out specimen. Focuses on clinicopathologic features and correlations so you can deal with the diagnostic problems you face every day.
For over 40 years Scheuer’s Liver Biopsy Interpretation has been an invaluable resource for the pathologist in practice and in training in helping to solve diagnostic problems at the microscope. Lavishly illustrated in full color throughout it covers all aspects of liver pathology from the normal, the hepatidities, childhood disease and neoplasms. Copious technical tips and diagnostic 'pearls' reflect the extensive experience and insight of the late Peter Scheuer and Jay Lefkowitch.. Throughout the text histopathologic features are correlated with clinical features to provide a practical account of how pathology impacts the diagnosis and management of liver disease. Well written, complete and concise quick reference.Helps the practicing and trainee pathologist solve diagnostic problems at the microscope. High quality color images complement the text throughout.Provides the user with a complete visual guide to each entity and assists in the recognition and diagnosis of any tissue sample under the microscope. Practical tips and “hands on advice from two of the world’s leading experts in liver pathology. Provides the trainee and general surgical pathologist with time saving diagnostic clues when dealing with difficult specimens. Glossary of frequently used terms and descriptions used in the pathology report contained at the end of the book. Useful quick reference for trainee pathologists and clinical hepatologists who may be unfamiliar with many of the terms and descriptions. Will assist in the writing and reading of a pathology report. A selection of a few general reading references at the end of each chapter.Directs the trainee or practitioner to the most relevant and authoritative sources of further information and study. A brand new chapter: "Practical Principles in Biopsy Assessment". Focus is on interpretation rather than a mere listing of pathological changes. The initial overview of the biopsy specimen provides critical clues to diagnosis and a highly illustrated guide to ddx will be of enormous help in avoiding diagnostic errors. Expanded coverage throughout, especially of liver tumours, pediatric fatty liver disease, neonatal cholestasis. Keeps the user apprised of the key areas of growth and development in diagnosis and interpretation. Histopathology correlated with molecular genetics and immunohistochemistry whenever clinically relevant. Keeps the user up-to-date with all of the latest tools for performing a complete and accurate diagnosis. Many new high-quality colour illustrations. Helps the user identify a wide variety of pathologic lesions. Text and images available online via Expert Consult.
Current Therapy in Reptile Medicine and Surgery is a valuable reference that emphasizes topics of real clinical relevance in reptile and amphibian medicine. With details on therapeutic regimens, this text also features coverage of infectious diseases, anesthesia, surgery, and advances in biology and conservation. Colorful illustrations showcase exotic animals, and numerous tables and figures provide quick access to essential information. "This is a great book for anyone interested in herptile medicine and surgery, worth every penny and I am sure will go on to become a regular series." Reviewed by: Jonathan Cracknell. Date: 25/07/2014 Selected topics of real clinical significance from the latest veterinary scientific literature explore today’s reptile and amphibian practice. A discussion of the most current theory and practical applications of diagnostic endoscopy in reptiles provides insight into minimally-invasive endoscopic procedures, including biopsy techniques. Expert contributors combine forces to bring you the most cutting-edge information available, offering authoritative and sometimes controversial opinions in particular areas. Expert contributors offer the most current thoughts on diagnosing new and emerging diseases, including a thorough review of molecular diagnostics. The latest therapeutics are discussed, and the most up-to-date formulary and library of normal clinical pathology values is provided. The most current and comprehensive discussion of amphibian medicine in print in the last decade!
This volume is an up-to-date review of the basic tests in gastroenterology. It provides a critical analysis of recently developed tests and a thorough appraisal of well-established methods. The text of this edition has been completely revised and re-organised. The selection of tests, their performance and the interpretation of results is presented in a logical and readily accessible format. Most of the chapters deal with the separate organ systems. Copious references to further reading are provided throughout the text, which is enhanced by clear illustrations. Topics covered include: Helicobacter pylori; upper digestive endoscopy; intubation; oesophagus; stomach; duodenum; small and large bowel; absorption; gastrointestinal bleeding; stool examination; pancreas; liver biochemistry, biopsy and radiology; gallbladder and bile ducts; pancreas; laparoscopy and the peritoneum.
Clinical Gastrointestinal Endoscopy, 2nd Edition, by Drs. Gregory G. Ginsberg, Michael L. Kochman, Ian D. Norton, and Christopher J. Gostout, helps you master the latest endoscopic techniques and achieve optimal outcomes. See how to perform key nuances with procedural videos at www.expertconsult.com in addition to 1,000 photographs, upgraded endoscopic images, and anatomical drawings both in print and online. Written by some of today’s most prestigious specialists and with many new and fully updated chapters, this resource equips you to diagnose and treat the full range of GI disorders with state-of-the-art coverage of bariatric surgery, therapeutic EUS, device-assisted enteroscopy, image-guided therapy, intramural endotherapy, and much more. Get comprehensive details on a wide breadth of topics including anatomy, pathophysiology, and therapeutic management options in addition to the latest GI procedures and technologies. Advance your knowledge on the rapidly evolving state of clinical gastrointestinal endoscopy with expert multimedia guidance from some of today’s most prestigious specialists. Master new procedures with updates on the endoscopic management of bariatric surgery; EUS as a tool to direct endoscopic therapies; device-assisted enteroscopy for deep exploration of the small intestine; image-guided therapy to help detect cancer earlier; intramural endotherapy including the new POEM procedure; and much more. Keep current with both new and emerging technologies including the management of upper gastrointestinal familial adenomatous polyposis syndrome and ampullary tumors; post-bariatric endoscopy and endoscopic therapy; endoluminal bariatric techniques, and intramural/transmural endoscopy. See how to perform key procedures step by step with endoscopic videos at www.expertconsult.com, and access the complete text, online-only references, and all the illustrations. View techniques more clearly with upgraded endoscopic images and step-by-step illustrations in most chapters.
The Guest Editors are providing comprehensive coverage of the clinical diagnosis, treatment, and management of Celiac Disease. Their authors are top experts in the field, and they have submitted state-of-the-art reviews. Topics inlclude: Clinical presentation of Celiac Disease in Adults and Children; The Irritable Bowel Syndrome--Celiac Disease Connection; Pathophysiology of Celiac Disease; Diagnosis of Celiac Disease; Histopathology in Celiac Disease; Management of Celiac Disease; Malignancy and Mortality in Celiac Disease; Gluten Sensitivity; Video Capsule Endoscopy in Celiac Disease; Refractory Celiac Disease; Celiac Disease in the Developing World; and Dietary Assessment in Celiac Disease.
Written by today s leading experts, Kirk's Current Veterinary Therapy, Volume XV keeps you completely current with the latest in disease management for dogs and cats. It uses a clear and practical approach to medical disorders; the typical chapter includes both a brief guide to diagnosis and a detailed discussion of therapy. You ll gain quick access to information such as critical care; infectious, toxicologic, and dermatologic disorders; and diseases of the gastrointestinal, cardiovascular, respiratory, urinary, reproductive, neurologic,and ophthalmologic systems. From editors John Bonagura and David Twedt plus hundreds of expert contributors, Kirk's Current Veterinary Therapy enhances your skills in evidence-based treatment planning. "For the practitioner who wants to keep abreast of current therapies for a wide range of topics, ... CVT is the perfect reference ." Reviewed by: Ryan Ong, WAVES Veterinary Hospital on behalf of Australian Veterinary Hospital, March 2015 Authoritative, easy-to-read coverage includes a brief approach to diagnosis with detailed discussions of the latest therapies. An organ-system organization and a convenient index make it easy to find solutions for specific disorders. Treatment algorithms help you manage patients with difficult medical problems. A handy Table of Common Drugs, updated by Dr. Mark Papich, offers a quick reference to dosage information. 365 illustrations depict the pathophysiologic basis for therapy or show the management of a defined condition. A companion website includes valuable information still relevant from CVT XIV, an index, and drug formulary, all fully searchable; a collection of 300 images; references that link to PubMed; and clinical references on laboratory test procedures and interpretation, normal reference ranges, conversion tables, and more. Concise chapters are only 2-5 pages in length, saving you time in finding essential information. Expert contributors and editors provide scientific, up-to-date coverage of clinically useful topics, including broad, traditional, and controversial subjects. References indicate related material from earlier volumes of Kirk’s Current Veterinary Therapy. NEW chapters cover the most important, emerging information on current diagnostic, treatment, and preventive challenges in today’s veterinary practice. A new section on feline and canine nutrition covers important issues in nutritional health. 50 new chapter authors join hundreds of expert international contributors, all of whom are leading authorities in their fields. NEW! Availability as Pageburst ebook allows you digital access to this volume along with your library of other Elsevier references.
Not another textbook for neuropathology! Yes, Our publishers helped us with this last problem by we hear you and feel your pain. In fact, that was our insisting on black and white photographs. We ini initial response when we were approached to write tially protested, noting that many recent textbook the book you are now holding. In surveying the reviews seemed to be primarily guided by whether expanse of currently available neuropathology illustrations were in color (good) or black and white textbooks, however, we came to feel that there was (bad). However, upon further reflection we accepted a place for a book that could combine our career this mandate as a blessing in disguise, allowing the experiences of trying to discern what is known (and reader to focus on differences in morphology, rather knowable) with the perennially proposed question, than tincture, as a guide to correct diagnosis. In fact, "What do we need to know?" Together we tried to one of us (M. e. ) has always been a fan of black and produce a book that would be practical, understand white photography, both in histologic atlases as well able, and to the point (minimizing reading time as in the immortal photographs of artists ranging from during intraoperative consultation). We have con Ansel Adams to Diane Arbus.
Written by the authorities in endoscopic surgery, this text presents all diagnostic and therapeutic endoscopic procedures in a single volume. The book covers all applications of this technology with particular emphasis on the role of endoscopy in the care of the individual patient and how the technique complements routine surgical practice. Well illustrated, with over 400 color photographs to aid in the interpretation of the procedures.